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摘要
多发性内分泌腺瘤病(multiple endocrine neoplasia,MEN)1型是一种常染色体显性遗传疾病,其特征为垂体、甲状旁腺、内分泌腺及胰腺中出现肿瘤。本文报道了1例出现严重休克症状的MEN1型病例。辅助检查提示:胃泌素瘤、垂体腺瘤 、甲状旁腺腺瘤。MEN1具有显著的家庭聚集性,合理运用基因检测手段对患者及其家属进行筛查,对于疾病的诊疗和预后具有重要意义。
Abstract
Multiple endocrine neoplasia type 1 (MEN1), an autosomal dominant genetic disorder, is characterized by the development of tumors in the pituitary, parathyroid, endocrine glands, and pancreas. It is also associated with an increased risk of breast cancer, as evidenced by studies indicating that female MEN1 patients have a higher relative risk of developing breast cancer compared to the general population. This article presents a case of MEN1 complicated by severe shock symptoms. Auxiliary examinations indicated the presence of gastrinoma, pituitary adenoma, and parathyroid adenoma. This disease exhibits a high degree of familial aggregation, and the judicious application of genetic testing for patients and their families holds significant importance for diagnosis, treatment, and prognosis.
关键词
多发性内分泌腺瘤病1型
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胃泌素瘤
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休克
Key words
Multiple Endocrine Neoplasia Type 1
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Gastrinoma
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Shock
龚帆, 邓阳欢, 傅华成, 米海淇, 江涛.
一例合并休克的多发性内分泌腺瘤病1型的病例报道[J].
实用休克杂志, 2026, 10(1): 56-58
Gong Fan, Deng Yanghuan, Fu Huacheng, Mi Haiqi, Jiang Tao.
Multiple endocrine neoplasia type 1 with shock: A case report[J].
Journal of practical shock, 2026, 10(1): 56-58 DOI:
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